Knowing the harm done to the body by alcohol, hard drugs, and even tobacco smoking, people often wonder how harmful cannabis in a weed dispensery is and whether marijuana affects the liver. In fact, hemp is a unique plant that can change a person’s mind but does not have a strong negative effect on his internal organs. This unique effect is due to the extremely low content of the active substances of marijuana in the herbal product. For example, to get a tangible effect of the main psychoactive cannabinoid called tetrahydrocannabinol (THC), you need only 5 mg, which is 0.005 grams.
At the same time, THC is a non-toxic compound. During the use of cannabis by mankind, not a single case of an overdose of cannabinoids has been registered, which would lead to a fatal outcome. Until now, even the exact lethal dose has not been established because, according to preliminary calculations, it should exceed the minimum dose by about 20,000-40,000 times. And it is very, very difficult to imagine that a person can use such an amount of marijuana at a time.
In addition, the pathological effect of cannabis on the internal organs of a person has not been revealed. To understand how marijuana and the liver interact, you should take a closer look at the intricacies of processing and the ways in which THC is eliminated from the body.
Metabolism of THC in the human body
After a person wants to buy hash online and a portion of THC enters his body, the metabolic process starts. At the first stage, tetrahydrocannabinol is converted into 11-OH-THC, identical in psychoactivity. In the next step, 11-OH-THC is already converted into the neutral acid THC-COOH. This compound is water soluble and is gradually eliminated from the body in the urine.
If THC entered the human body by inhalation, that is, through the lungs, then about 65% of the total THC is processed and excreted in a similar way. If a person has used marijuana orally, that is, with food, then the percentage will be even higher because the venous blood flow from the gastrointestinal tract passes through the liver, where the process of decay of active substances immediately starts.
The rest of the cannabinoids are roughly evenly distributed among dozens of other metabolic patterns that are no longer as significant. All of them are inherently non-toxic and do not have a detrimental effect on the body and general well-being of a person, such as, for example, alcohol metabolites in a hangover. This means that the breakdown products of cannabinoids do not cause any chemical poisoning.